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ea0041ep84 | Adrenal medulla | ECE2016

Pheochromocytoma/paraganglioma: Histopathological features as clue to the underlying germline mutation in these genetically heterogeneous tumors

Roy Maitrayee , Agarwal Shipra , Sharma Mehar Chand , Gupta Poonam , Khurana M L , Khagawat Rajesh , Tandon Nikhil

Introduction: Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are rare neuroendocrine tumors arising from chromaffin cells within adrenal medulla and autonomic paragranglia respectively. Recent evidences show that nearly one-third patients harbour germline mutation, namely in von Hippel-Lindau (VHL), REarranged during Transfection (RET), neurofibromatosis type 1 (NF 1) and succinate dehydrogenase (SDH) complex genes. However, the tumor morphology arising in various syndrom...

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Pheochromocytoma/paraganglioma: Histopathological features as clue to the underlying germline mutation in these genetically heterogeneous tumors

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